Comedian Nikki Glaser is a big supporter of anyone taking Ozempic.
The 40-year-old comedian appeared on the March 24 episode of The Tonight Show when host Jimmy Fallon asked what her thoughts were about the trendy weight-loss aid.
Ozempic is an FDA-approved prescription medication to treat type 2 diabetes. The medication — taken weekly by injection in the thigh, stomach or arm — is a brand name for semaglutide, which works in the brain to impact satiety.
The drug has gained popularity in and out of Hollywood over the last few years as many people turn to it for weight loss, even when not medically necessary.
“Oh, I love it, I love it. I’m like, do it, do it. I have no judgment,” Glaser said. “If you want to do Ozempic, hell yeah, girl. I want people to feel more comfortable talking about doing it, because I feel like there’s, like, this shame — and the shame is only from thin people who want you to stay fat. Like that’s really where it’s coming from.”
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“They are so mad that you’re getting thin now, because that’s all they have, right? They are so mad, but they can’t say it. They just go, ‘No! You’re stealing medicine from diabetics who need it.’ Like, that’s their excuse,” she continued. “It’s suddenly all these thin, white women are like ‘diabetics need their meds.’ No, I think you’re upset that Kathy Bates has a thigh gap. That’s more what it could be about, I think.”
During the show, Glaser also defended plastic surgery, joking about getting a facelift in August 2026.
“I have no problem with that. You gotta do it subtly. You have to do it so they go, ‘What’s she doing?’ And you can go, ‘Just meditating more,’” she quipped. “That’s what they say, you know. I’m drinking more water. I’m just working on my gut health so my brow has been lowered two inches.”
“That’s what you do, that’s how you get away with it,” she joked as Fallon laughed hysterically. “I think it’s a wise investment. There’s kind of a stigma around getting face work or investing in your beauty and doing all these procedures. And there’s maybe a little bit of sadness to it, but I kinda also am like well, it makes my life better. People treat you better when you’re hotter. It’s just a fact. It’s a sad fact of life.”
